PTC has made much progress at reducing railroad operational risks, but optimizing safety and efficiency never stops. As railroads continue to innovate, further improvements and operational advancements will be deployed. Safety HMI (human-machine interface) technology, combined with continued human factors design considerations, can mitigate known hazards and safely allow for expanded functionalities. Railway Age Editor-in-Chief William C. Vantuono discusses the expanding scope of automation and increasing recognition of HMI, in terms of safety-critical train control interfaces, with Blake Kozol, CEO, Deuta America Corporation; Kelly Nichols, Principal System Engineer and Project Engineering Lead, Collins Aerospace; Carolynn Johnson, Human Factors and Research Manager, Daedalus; Ryan McKinley, President and Safety Engineer, Vital Assurance; and Eileen Reilly, CEO, Global Train Services LLC. Podcast sponsored by Deuta America.